Table of Contents

Cannabis for Nausea

Dani Walton
Dani Walton
Photo Cover

Discover the Best Cannabis for Nausea: High CBD strains like ACDC, Harlequin, and Cannatonic have been shown to be effective. If you are experiencing nausea, you may be wondering if cannabis can help. While research on the topic is limited, some strains of cannabis have been shown to help reduce nausea and vomiting. In this article, we will explore the best cannabis strain to help nausea and how it works.

Cannabis contains over 100 compounds known as cannabinoids, which interact with the body’s endocannabinoid system. Two of the most well-known cannabinoids are THC and CBD. THC is the compound responsible for the “high” associated with cannabis, while CBD is non-intoxicating and has been shown to have therapeutic benefits for a range of medical conditions, including nausea.

The best cannabis strain to help nausea is likely one with a high CBD content and lower THC content. This is because CBD has been shown to have anti-nausea effects, while high levels of THC can actually worsen nausea in some people. Some strains that may be helpful for nausea include ACDC, Harlequin, and Cannatonic.

How Scientists Believe the Body Regulates this Condition. The endocannabinoid system (ECS) is believed to play a crucial role in regulating nausea. Imbalances in the ECS may lead to symptoms like nausea. Cannabis contains chemical compounds (Cannabinoids) that interact with the ECS receptors, offering potential relief.

One notable compound with anti-vomiting properties is tetrahydrocannabinol (THC). THC is commonly known as the main psychoactive cannabinoid in cannabis, and is also the main ingredient in an anti-nausea drug called dronabinol.

FDA-Approved Dronabinol: A Synthetic THC for Reducing Nausea and Vomiting. Since 1985, dronabinol has been FDA-approved for its effectiveness in reducing nausea and vomiting caused by cancer treatments such as radiation and chemotherapy.

In the 1980s, the drug was also used to combat appetite loss and anorexia associated with HIV and AIDS. Today, dronabinol remains a prescription-only medication used for managing cachexia in patients with AIDS/HIV or cancer.

The Role of Other Cannabinoids in Relieving Nausea

While other cannabinoids in cannabis like CBD may provide milder effects on nausea, cannabinoids like CBG may counteract the anti-nausea effects of CBD and require higher doses to impact overall anti-emetic effects. However, THC is typically preferred by most people for treating nausea, and using a variety of cannabinoids and other compounds is often recommended.

Choosing the Right Cannabis Delivery Method for Nausea Relief

Some individuals prefer smoking cannabis to manage their nausea, while others turn to topical products applied to the stomach or head (for migraines). Cannabis edibles may not be suitable for those experiencing difficulty with eating or maintaining a healthy appetite. For those seeking oral consumption of cannabis for nausea, a drop or two of tincture may be a more suitable alternative to edibles.

Choosing-the-Right-Cannabis Delivery Method for Nausea Relief

Rapid Relief from Nausea with Cannabis Consumption

Regardless of the chosen delivery method, most individuals report immediate relief from nausea. A study by researchers at the University of New Mexico found that over 96% of the 2,220 participants experienced relief from nausea within one hour of consuming cannabis. Flowers and concentrates were the most effective products in the study, while edibles were found to be the least effective.

Caution When Using Cannabis for Nausea Treatment

Possible side effects and severe CHS disorder. It is crucial to be aware that some individuals may experience nausea as a side effect of cannabis. Additionally, cannabis hyperemesis syndrome (CHS) is a rare but severe disorder that may result from long-term cannabis use and involves frequent, uncontrollable vomiting without a cure. Consult with a physician before using cannabis to treat nausea and vomiting.

Caution When Using Cannabis for Nausea Treatment

In an investigation carried out by the researchers Linda A Parker, Erin M Rock, and Cheryl L Limebeer, called “Regulation of nausea and vomiting by cannabinoids” and published by the British Journal Pharmacology, some results were obtained that we will see below.

The effect of cannabinoids on nausea in animals.

In simple terms, nausea is more difficult to treat than vomiting with the newer antiemetic drugs and remains a major problem in chemotherapy treatment and as a side effect of other drug therapies, such as antidepressants. Although the emetic response caused by cisplatin is blocked in the ferret by a 5-HT3 receptor antagonist, c-fos activation still occurs in the AP, suggesting that action here may be responsible for some other effects of cisplatin. cytotoxic medications, such as nausea or reduced food intake.

In rats, gastric afferents respond in the same way to physical and chemical stimulation (intragastric copper sulfate and cisplatin) that precedes vomiting in ferrets, presumably resulting in nausea before vomiting. In addition, the 5-HT3 antagonists that block vomiting in ferrets also interrupt this anterior neural afferent reaction in rats.

The effect of cannabinoids on nausea in animals.

That is, in the rat, the nausea detection mechanism is present, but the vomiting response is absent. Nauseogenic doses of cholestokinin and LiCl induce specific c-fos expression patterns in the brain stem and forebrain in female ferrets that are similar to c-fos expression patterns in rats. In a classic review article, Borrison and Wang (1953) suggest that the inability of rats to vomit can be explained as a species-adaptive neurological deficit and that, in response to emetic stimuli, the rat displays autonomic and behavioral signs. corresponding to the presence of nausea, called prodromata (salivation, pupillary dilation, tachypnea and tachycardia).

The effect of cannabinoids on nauseous in rat

Studies have shown that a small amount of Δ9-THC can interfere with the appearance and manifestation of a conditioned yawn in rats caused by cyclophosphamide (Limebeer and Parker, 1999). It has also been found that a potent substance called HU-210 (0.001-0.01 mg/kg) can reduce a conditioned yawn caused by LiCl (Parker and Mechoulam, 2003; Parker et al., 2003).

This effect can be reversed by a substance called rimonabant, suggesting that HU-210 acts through CB1 receptors. If rimonabant is administered 30 minutes before a conditioning trial, it will not cause the yawn by itself, but it can make LiCl cause the yawn more easily.

This has been reported in studies on vomiting (Van Sickle et al., 2001; Chambers et al., 2007). In one study, it was reported that AM251, another CB1 antagonist/inverse agonist, did not cause vomiting by itself, but it could make an emetic stimulus cause vomiting in a ferret

Recently, solid evidence was found that the endocannabinoid system can act as a regulator of dizziness. This is because extending the action of anandamide with a drug called URB597, which inhibits the FAAH enzyme, also disrupts the formation of conditioned reactions in rats caused by LiCl (Cross-Mellor et al., 2007). Rats treated previously with URB597 (0.3 mg·kg−1, i.p.) 2 hours before a saccharine-LiCl association showed reduced conditioned yawning reactions in a subsequent drug-free trial.

Rats that received the combination of URB597 (0.3 mg·kg−1, i.p.) and anandamide (5 mg·kg−1, i.p.) showed an even greater suppression of conditioned yawning reactions. Although FAAH inhibition leads to an elevation of a variety of fatty acids that act on different receptors, the effect of URB597 on conditioned dizziness was reversed by AM251, indicating that it was mediated by CB1 receptors.

The effect of cannabinoids on nauseous in rat

Basically, scientists have learned a lot about how marijuana works in our bodies to stop feeling sick and throwing up. They’ve studied it in small animals like ferrets and shrews and found that it affects a specific part of the brain. These animals have helped researchers understand the benefits of using marijuana to treat nausea, which can be a harder problem to solve than just vomiting.

Recently, they’ve also seen that marijuana can help with a condition called AN. Studies on rats and another small animal called S. murinus have shown that two chemicals in marijuana, THC and CBD, can keep them from getting sick again after being in a certain place that made them sick before.

Despite conventional drugs effectively controlling vomiting in most chemotherapy patients, dealing with nausea remains a challenge. Nausea can be more distressing than vomiting as it’s a constant feeling. Sadly, this can even cause some patients to stop their chemo. But studies have shown that cannabis compounds may be helpful in reducing nausea in chemotherapy patients, both in animal testing and in human clinical trials.

Studying vomiting has helped us understand how it works in the body (Hornby, 2001), but the science behind nausea is still a mystery (Andrews and Horn, 2006). Testing for nausea in lab animals has been tough because there isn’t a proven model that accurately reflects the symptoms in humans.

For years, researchers have tried using rats that avoid certain tastes as a sign of nausea, but this has been proven to be flawed because even treatments without nausea can cause taste avoidance (Parker et al., 2008). However, recent research suggests that the disgust response in rats when exposed to a flavor or context associated with illness (Parker et al., 2008, Rock et al., 2008) can be a reliable and sensitive measure of nausea. This model could be useful in learning more about the biology of nausea and how the endocannabinoid system may play a role in controlling it.

Best Cannabis Strain to Help Nausea

Effective Strains for Nausea and Vomiting Relief: A Guide to Popular Cultivars. For medical users seeking relief from nausea and vomiting, these three strains (cultivars) have proven helpful. With unique benefits, ranging from mood-boosting to calming, these strains are worth considering.

However, it’s important to note that any cannabis strain containing anti-emetic cannabinoids such as THC, CBD, THCV, and CBN in high doses can aid in reducing nausea and vomiting. Everyone’s experience is unique, and a different strain may work better for an individual’s specific nausea symptoms. Here are some of the most widely used cultivars with a history of anti-emetic properties

Critical Nicky Kush – Cannabis For Nausea

Critical Nicky Kush is a cannabis strain that has gained popularity for its relaxing and calming effects. This genetics is derived from the cross between Hybrid, Kush strains, North American and Canadian, resulting in a plant with a high concentration of THC and a moderate level of CBD. Users report its effects include a feeling of deep relaxation and relief from stress and anxiety. Furthermore, Critical Nicky Kush is known to be effective in managing nausea and other symptoms of illness, making it an excellent choice for medical patients.

Critical Nicky Kush

The aroma and flavor of Critical Nicky Kush are intense and sweet, with notes of terpenes of tropical fruits and wood. Flowering time is around 8-10 weeks, and the plant can produce a generous crop (42 oz/plant outdoor) of high-quality resin. When it comes to THC and CBD levels, Critical Nicky Kush can contain up to 18%-25% THC and 2% CBD. This high THC content makes her an ideal choice for experienced users, while her low CBD level makes her a good choice for medical patients seeking relief without overly high psychoactive effects.

CBD Stephen Hawking Kush – Weed For Nausea

This genetics called CBD Stephen Hawking Kush is a cannabis variety rich in CBD, with a ratio of 1:1 because it contains CBD levels that are in a range of 10%-13% similar to THC levels that are between 10%-12 %. As we already pointed out in the text, researchers have discovered that when using genetics rich in CBD, higher doses are needed, however, as this is a genetic that also has good THC levels, we believe that perhaps large doses are not needed. dosage for medicinal users. In any case, it is always good to consult with the treating physician to obtain an informed and professional opinion.

CBD Stephen Hawking Kush
CBD Stephen Hawking Kush

Other characteristics of CBD Stephen Hawking Kush is its good production since it can reach up to 21 oz/plant outdoors and indoors you can get about 1.31 oz/ft2 of buds. On the other hand, CBD Stephen Hawking Kush will stimulate your appetite, and relaxes you, which is not combined with its delicious berry flavor, with earthy aftertastes, and hints of wood.

Somango Fast Version – Best Cannabis Strain to Help Nausea

With a potency of 16%-20% THC, Somango Fast Version becomes a variety of weed indicated for medicinal users who seek to relieve nausea since its effects are sedative and manage to calm users. For this reason as well, it is good for medicinal users who need to control chronic pain, arthritis and insomnia. But that’s not all, because users can also have a good amount of raw material if they want to make their own medical cannabis oils at home, since Somango Fast Version delivers incredible yields outdoors that reach up to 52 oz/plant and in indoors, the benefits are no less to the contrary, you can get about 1.47 oz/ft2 of rich, resin-coated buds.

Somango Fast Version

To the above, you must add that Somango Fast Version only needs 60 to 70 days to be ready to flower indoors, during which time you will harvest sweet-tasting buds with mango-like fruity aftertastes. Another important characteristic is that this genetics is low in CBD and very rich in THC, therefore we do not recommend you go over the limits or abuse consumption levels because it can cause you some unwanted effects. On the contrary, we recommend you consult with your treating doctor so that you have a good orientation and get the best possible results.

Strains featured in this article:

Dani Walton

Dani Walton is a highly accomplished cannabis expert and entrepreneur hailing from the Bay Area. With an impressive track record spanning over 20 years, Dani has amassed a wealth of experience in the cannabis industry. Her journey has taken her across the globe, as she traveled with the executive team of Harborside for more than 11 years, passionately advocating for the positive impacts of the cannabis plant.

During her tenure at Harborside, Dani excelled in managing wholesale and distribution for Harborside's farm, while also playing a pivotal role in the development of their in-house brand, Key. Following her departure from Harborside, Dani embarked on a new venture, co-founding NXTLVL, a women-owned concentrate delivery service that quickly gained recognition and Agris Farms. A beautiful 5 acre light dep farm located in Woodland, near Sacramento.

Her extensive knowledge encompasses the latest consumer trends, cannabis sales, extraction techniques, cultivation methods, new brands and products, as well as the evolving science of cannabis medicine. Recognized as a respected authority in the industry, Dani has served as a judge for esteemed cannabis competitions such as Chalice, High Times, Dab- A- Doo, The Organic Cup and The Emerald Cup. Her expertise and insights have been sought after by renowned publications and media outlets, including Forbes, The Guardian, The Independent, and many others.

With her remarkable background and unwavering commitment to advancing the cannabis industry, Dani Walton stands as a true pioneer and an influential figure in the field.

Read More Read Less

Related Articles

Explore our shop

Blimburn OG Seeds