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what are cannabinoids?

Cannabinoids are a class of chemical compounds present in the cannabis plant that interact with cannabinoid receptors in the human body and produce different effects in the body. The best known cannabinoids are THC and CBD, but there are many others that have recently been discovered and are being investigated for their therapeutic potential.

In this guide we are going to discover the qualities of each of the cannabinoids that exist, their properties whether they are for recreational or medicinal use. For the same reason, do not move as you will learn things that you may not know and you will see what science says.

The different cannabinoids

THC, or tetrahydrocannabinol, is the main psychoactive cannabinoid present in marijuana and is responsible for most of the psychotropic effects associated with cannabis use. THC binds to cannabinoid receptors in the brain, producing effects such as increased appetite, relaxation, euphoria, and perception shifting.

THC Cannabinoid

CBD, or cannabidiol, is another of the best-known cannabinoids and is known for its medicinal properties. Unlike THC, CBD is not psychoactive and does not produce psychotropic effects. Instead, CBD has been shown to have analgesic, anti-inflammatory, and anti-anxiety properties, and its potential for the treatment of different conditions such as chronic pain, anxiety, and sleep disorder is being investigated.

In addition to THC and CBD, there are many other cannabinoids present in the cannabis plant that are being studied for their potential therapeutic benefits. Some of these cannabinoids include CBG, CBN, and THCV.

CBG, or cannabigerol, is a non-psychoactive cannabinoid that has been shown to have anti-inflammatory properties and may be useful in the treatment of glaucoma and other eye disorders. Its potential for the treatment of cancer and other serious diseases is also being investigated.

CBG Cannabinoide

CBN, or cannabinol, is a cannabinoid that is formed when THC oxidizes and has been shown to have sedative and pain-relieving properties. Its potential for the treatment of insomnia and other sleep disorders is being investigated.

THCV, or Tetrahydrocannabivarin, is a cannabinoid found in some varieties of cannabis and has been shown to have properties that may be useful in appetite control and the treatment of obesity. Its potential for the treatment of diabetes and other metabolic diseases is also being investigated.

What say the science about cannabinoids?

Cannabinoids can have different effects in the body, and there are many studies investigating their potential benefits and risks. Here are three different studies investigating cannabinoids:

 A study published in “The New England Journal of Medicine” in 2018 evaluated the use of the cannabis plant to treat the symptoms of multiple sclerosis. The researchers found that cannabis significantly improved the participants  quality of life and reduced the intensity and frequency of attacks.

In 2014 a study published in the journal Psychopharmacology investigated the use of the cannabinoid CBD in the treatment of generalized anxiety disorder. The researchers found that CBD was effective in reducing anxiety and improving sleep in the participants.

cannabinoid CBD

Additionally, a 2018 study published in the journal PLoS ONE investigated the use of the cannabinoid THC to treat chronic pain in fibromyalgia patients. Researchers found that THC significantly reduced participants’ pain and improved sleep quality.

Another study published in the journal “Psychopharmacology” in 2016 investigated the use of cannabinoids to treat heroin addiction. The researchers found that THC and CBD significantly reduced participants’ heroin use, as well as craving for the drug.

One study published in the journal “JAMA Pediatrics” in 2018 investigated the use of THC during pregnancy and the possible impact on fetal development. The researchers found that THC use during pregnancy was associated with an increased risk of preterm birth and low birth weight. THC was also found to be associated with an increased risk of attention problems and hyperactivity in children as they grew older.medicines.}

These are just a few examples of the many studies that have investigated cannabinoids. There is much more work to be done to fully understand the effects and potential therapeutic uses of cannabinoids.

Advantages and disadvantages of cannabinoids

Some cannabinoids, such as THC (tetrahydrocannabinol) and CBD (cannabidiol), have been investigated for their potential therapeutic benefits. However, there are also risks and drawbacks associated with the use of cannabinoids. Here are three pros and three cons of cannabinoids:


Pain relief: Some cannabinoids, such as THC and CBD, have been shown to be effective in relieving pain in some studies. This can be helpful for people who suffer from chronic pain, such as fibromyalgia or back pain.

Reduction of anxiety and depression: Some studies have found that CBD can be effective in treating anxiety and depression.

Sleep improvement: THC and CBD can help improve sleep in some people.



Dependence risk: Prolonged use of cannabinoids, especially THC, can lead to dependence. This means that the person may feel compelled to use cannabinoids to feel good or to avoid withdrawal symptoms.

Side Effects: Some common side effects of cannabinoid use include dizziness, nausea, dry mouth, and fatigue.

Drug interaction: Cannabinoids can interact with other drugs you may be taking, including certain prescription drugs and supplements. This can increase the risk of side effects or change the way the medicines work. It is important to talk to a doctor or pharmacist before using cannabinoids if you are taking other

effects of cannabinoid

The dangerous synthetic cannabinoids

Synthetic cannabinoids are chemical compounds that are made in the laboratory and have a similar chemical structure to the natural cannabinoids found in the cannabis plant. These synthetic cannabinoids are often used to mimic the effects of natural cannabinoids and are sold as a powder, liquid, or as part of products made to be smoked or vaped.

Synthetic cannabinoids can act on the body’s endocannabinoid system, which is a system that involves a series of cannabinoid receptors and endogenous cannabinoids found in the brain and other organs of the body. When synthetic cannabinoids act on these receptors, they can produce effects ranging from relaxation and euphoria to altered perception, change in time and memory, and increased appetite.

Syntetich Cannabinoids

However, synthetic cannabinoids can also have adverse effects and can be dangerous to health. Common side effects of synthetic cannabinoids include nausea, vomiting, rapid heartbeat, hypertension, agitation, hallucinations, and psychosis. They can also lead to an increased risk of accidents and injuries due to impaired perception and coordination. In some cases, synthetic cannabinoids have been linked to overdose deaths. Therefore, it is important to exercise caution when using synthetic cannabinoids and to follow the manufacturer’s and medical professional’s instructions.

The endocannabinoids and the endocannabinoids system

The endocannabinoid system is a communication system in the body that involves a series of cannabinoid receptors and endogenous cannabinoids found in the brain and other organs of the body. Cannabinoid receptors are proteins found in the cell membrane that are activated when bound to endogenous or exogenous cannabinoids, such as naturally occurring cannabinoids found in the cannabis plant.

The endocannabinoid system has a variety of functions in the body, including the regulation of pain, inflammation, stress, sleep, appetite, and memory. It may also have a role in modulating the immune response and regulating blood pressure.

The naturally occurring cannabinoids in cannabis, such as THC and CBD, can interact with the endocannabinoid system and produce a variety of effects in the body. THC, for example, binds to CB1 cannabinoid receptors, which are found primarily in the brain, and can produce effects such as increased appetite, relaxation, and impaired perception and memory. CBD, on the other hand, binds to CB2 cannabinoid receptors, which are found primarily in the immune system, and may have anti-inflammatory and pain-relieving properties.

Endocannabinoid System

Now, almost all organisms in the animal kingdom produce endocannabinoids. They are natural endogenous ligands produced by animal and human organisms that bind to cannabinoid receptors. Endocannabinoids and cannabinoid receptors form the endocannabinoid system, which is involved in various physiological processes (eg, modulation of neurotransmitter release, modulation of pain perception, cardiovascular, gastrointestinal, and hepatic function).

The two most important endocannabinoids discovered are anandamide (N-arachidonoylethanolamine, ANA) and 2-arachidonoylglycerol (2-AG). Endocannabinoids are molecules that act as natural keys for the two main cannabinoid receptors, CB1 and CB2, leading to their activation and subsequent actions. CB1 is found primarily in the central nervous system and is responsible for the effects of neural processes and psychoactive “side effects”. CB2 is found primarily in the immune system and is responsible for immunomodulatory effects. CB2 receptors have recently been identified in microglia of the central nervous system and appear to be present in certain neurons as well, but today this remains a highly controversial and debated topic.

The most rich cannabis seeds  in Cannabinoids

As we have already said, among the best-known cannabinoids we can find THC, CBD and there are also other less popular ones such as CBN, THCV and also CBG, each one of them fulfills a different function. Because of this, we are going to leave you some recommendations for the best seeds and the richest weed strains that contain these cannabinoids. With this you will be able to grow cannabis plants from which you will obtain flowers high in cannabionoids, which can help you for medicinal use.

Mamba Negra CBG

La Mamba Negra CBG is a photo dependent and feminized cannabis variety that contains a high level of cannabigerol, reaching 10%-13% of CBG. This CBG-rich variety is non-psychoactive and has great medicinal properties, such as reduction of pain and inflammation, helps in the management of stress and anxiety and can also help with the improvement of immune system function. It can even have positive effects on the skin and hair, among other benefits.

Mamba Negra CBG Marijuana Plant

Regarding the effects produced by Black Mamba CBG, its users say that it produces feelings of joy, stimulates creativity and leaves people in a cloud of well-being. However, it is important to note that the effects of cannabis can vary significantly from person to person and depend on many factors, such as the dose and method of consumption. 

With Mamba Negra CBG you will harvest yields of 0.98 oz/ft2 indoors and up to 24 oz/plant outdoors in a short time, since the flowering time of this variety is only 50 -55 days, although there may also be phenotypes that take 8-10 weeks. In addition, since it is an easy-to-grow genetic, it is suitable for novices who will benefit because Mamba Negra CBG strain helps you control fatigue, lowers stress levels and reduces muscle spasms.

Blackberry Pie

This mostly indica and feminized variety called Blackcherry Pie is rich in the cannabinoid THC reaching levels of 18%-20% and being of great help for medicinal use. Some of the diseases that can be counteracted with Blackberry Pie strain are old age, pain caused by migraines and also fatigue. In addition, together with its rich berry flavor, with notes of blueberry and citrus touches, Blackberry Pie helps control and reduce chronic pain, stimulates the appetite and can even induce sleep. All of the above makes this variety an authentic gem for medicinal users who suffer from pathologies such as Cancer and who present some symptoms such as those already described.

Blackberry Pie strain

In relation to the cultivation of Blackberry Pie we can say that it is an easy-to-grow genetics from which we can obtain up to 1.47 oz/ft2 of buds indoors and about 24 oz/plant for outdoor cultivation with a flowering time of 8 to 10 weeks. To maximize the yields of this genetics, it is best to make LST and also apply the SOG technique, with which plants with a dense, compact, very heavy central bud full of buds are obtained.

CBD Chemdog #4

We already mentioned that CBD is also one of the most studied cannabinoids today. This is why we are going to talk about CBD Chemdog #4, genetics with a 1:1 ratio, that is, it has 1 part of CBD and 1 part of THC because it concentrates CBD levels of 6%-7% and THC levels of 6%-7%. For medicinal users, CBD Chemdog #4 strain will help them fall asleep and eliminate insomnia. In addition, you will reduce the intensity of chronic pain and relieve arthritis discomfort.

CBD Chemdog #4

To maximize the yields of CBD Chemdog #4 you can apply cultivation techniques such as SCROG, promoting the stretching of the arms and helping the plant receive better lighting. You can also use the SOG technique with which you will increase the yield of the central stem of CBD Chemdog #4. Among the flavors given off by the CBD Chemgod #4 buds, its citric lemon taste stands out with notes of pine and wood and sweet aftertastes.